Top Nutrition Coaching is fully dedicated to providing its readers with transparent, accurate, and compassionate information that applies to individuals from every demographic. Our nutritionists adhere to specific guidelines when creating content to ensure that all published materials are most advantageous to our readers. Top Nutrition Coaching has a no-tolerance policy regarding plagiarism.
All materials published by Top Nutrition Coaching adhere to the criteria outlined below:
At Top Nutrition Coaching, we only recommend brands we trust, all of which are selected and reviewed by our dietitians. We may receive compensation for this content, which was created in partnership with Live it Up.
Gut health is the next frontier in the wellness industry, with products ranging from drinks to capsules. And as a registered dietitian nutritionist, I fully understand the importance of keeping our digestive tract running smoothly.
Not only does our gut impact our digestion and nutrient absorption, but it can also impact our mood, immune system, and sleep. I also know how confusing it can be to choose a supplement that fits your individual needs. Does the product really do what it says, and how can you tell? I’m here to break it all down for you so that you can choose the best supplement for your digestive needs.
In this article, I’ll focus on the five best gut health supplements, exploring the pros and cons of these top options so that you can walk away confident in your choice.
Though all five supplements in this article are excellent options, spanning from powders to capsules, these top three won out for providing excellent gut health- supporting ingredients.
The digestive tract is incredibly complex, with many factors influencing its health.
While most people think about probiotics, fiber, and digestive enzymes as the primary supplements that help support gut health, the amount and variety of vegetables consumed per week also play a huge role in a balanced gut microbiome. And yet, eating veggies is where most Americans fall short in their everyday diet. This fact plays a critical role in how I, as a registered dietitian, think about gut health supplements.
Here’s a look at our five gut health supplement picks.

Live it Up is a company focused on providing high quality superfood formulas that help increase your intake of nutritious, antioxidant-packed plants and the health benefits they may confer.
Price per serving (with subscription): $1.33
Live it Up claims that Super Greens aids gut health, digestion, and bloating support. It also supports immune function and energy.
Super Greens not only goes through rigorous third-party testing for microbes, heavy metals, pesticides, herbicides, toxins and allergens, but is also produced in a facility that is certified for Good Manufacturing Practices.
Additionally, this greens powder is made with all organic vegetables, sourced from across the globe and the U.S., helping ensure only the highest quality. Live it Up Super Greens is also free of fillers and preservatives; artificial colors, flavors, and sweeteners; as well as added sugar.
Vegetables. With more than 16 plants, Super Greens helps to boost vegetable intake closer to the recommended servings per day. Research indicates that people who eat a wider variety of plants each week have a more diverse and healthy gut microbiome. Since Super Greens contains plants like oatgrass and nopal cactus that are not normally consumed, it can up the plant variety in the diet, therefore supporting gut health.
Probiotics. Super Greens contains 5 billion CFUs of clinically studied probiotics, including Lactobacillus acidophilus, Lactobacillus casei, Bifidobacterium bifidum, and Bifidobacterium lactis. These probiotic species have been shown to work synergistically, helping to enhance their biological activity.
Fiber. While Super Greens does not add prebiotic supplements like other greens powders, it does contain 3 grams of dietary fiber naturally derived from its ingredients, many of which are rich in prebiotic fibers like nopal cactus, barley and wheat grass, kelp, and alfalfa leaf.
Digestive enzymes. Super Greens contains the following plant-based digestive enzymes: papain, bromelain, and a protease blend.
Nutrition Fact: Research is finding that the more plants you eat, the better your gut health. A new study shows that people who eat at least 30 different plants throughout the week have more of the ‘good’ gut bacteria, compared to those who just eat 10.
Since Super Greens is a powder, it must be mixed with any beverage or food of your choice, including water, a smoothie, or juice. This greens powder comes in two flavors: Original with a touch of mint, and Wild Berry, with a citrus, berry zing. Both options are subtly and naturally sweetened with monk fruit.
Super Greens is my top choice because it’s the full package when it comes to gut health supplements. With more than 16 greens, dairy-free probiotics, 3 grams of fiber that includes prebiotic sources, as well as digestive enzymes, this well-rounded greens powder is an excellent way to keep your gut supported and regular.

VSL has been producing quality, high potency probiotics for two decades, and their VSL#3 probiotic supplements have been extensively studied.
VSL#3 price per serving (with subscription): $1.97 per serving for one tablet, twice day
The company states the VSL#3 formula is scientifically formulated to manage digestive well-being and gastrointestinal conditions.
VSL#3 is classified by the FDA as a medicinal food. This means the product has been independently tested for what’s inside the capsule and produced in a facility that is GMP certified, both of which are reassuring signs of quality. But it’s good to be aware that VSL#3 capsules (like most supplements) don’t undergo the same testing or pre-approval process as a pharmaceutical drug.
Probiotics are live bacteria that may impact human health when consumed in high enough doses. VSL#3 contains 8 strains of probiotics from 3 species:
VSL’s research on these live microorganisms indicate they work well synergistically, have good survival rates, and are guaranteed until the expiration date.
Additionally, a narrative review of VSL#3 demonstrated a positive link between consumption of VSL#3 capsules and composition of the intestinal gut flora.
Because this product is a capsule, it is quite convenient. However, note that it must be refrigerated and taken with a cold beverage and/or food to help ensure the probiotics survive. If taking capsules does not work well for you, VSL#3 also comes in a powder, though you’ll pay more.
VSL#3 is a high-potency daily probiotic supplement backed by research that would make a great addition to the supplement routine of someone looking to focus on aspects like bloating, immune function, or getting more “good” gut microbes in your microbiome.. While this probiotic supplement may meet the needs of individuals who are already getting sufficient fiber and vegetables, those seeking a formula that includes other gut-benefiting ingredients like digestive enzymes and prebiotics may not find it comprehensive enough.

Florastor is a probiotic supplement that has been around for over 20 years. Owned by the company Biocodex, Florastor is the only probiotic on the market that contains the yeast-based probiotic Saccharomyces boulardii, for which Biocodex owns the exclusive rights.
Price per serving (with subscription on Amazon): $1.76
Florastor’s website cites several potential health benefits, including:
Florastor has been on the market for over two decades, and the yeast-based probiotic Saccharomyces boulardii that it contains has been studied for almost 70 years. With that said, it is unclear if the product goes through third-party testing, though it is produced in a GMP-certified facility.
This gut health supplement is a synbiotic, meaning it contains both probiotics as well as prebiotics. This is an important combination as prebiotics are the ideal fuel for probiotics.
Saccharomyces boulardii is yeast probiotic. Research indicates that this probiotic has many potential health benefits and helps support health of the gastrointestinal tract. Florastor states they do not measure their supplement in CFUs because a yeast probiotic cell size is up to 10 times larger than bacteria-based probiotics. This makes between-brand comparisons more difficult. However, I was able to find out that Florastor contains about 5 billion CFU.
Chicory root fiber, also known as inulin, is a prebiotic fiber, which feeds the good bacteria in your gut.What I like about Florastor Advanced Pro + Pre is that it contains more prebiotics than many other synbiotic supplements on the market.
Nutrition Fact: Some people have difficulty digesting fermentable carbohydrates. If you’re someone with a sensitivity to fermentable carbohydrates, know that inulin falls into this category (it’s a fructan) and it’s best to speak to a healthcare professional to understand whether the product will suit you.
As a capsule, Florastor is quite convenient and portable. Plus, it does not need to be refrigerated. If you are unable to swallow the capsule, the company recommends opening the capsule by twisting the two ends and mixing with a cold or room temperature food like yogurt or applesauce.
Florastor Advanced Pro and Pre combines both prebiotics with probiotics, which gives it a leg up on solo probiotic supplements. Its use of a yeast-based probiotic, which is backed by years of research, makes it a solid choice. However, if you’re looking for a supplement that targets all aspects of gut health, this one somewhat misses the mark.

Thorne prides themselves in clean, high-quality supplements aimed to help people reach their wellness goals.
Price per serving: $1.35 (monthly subscription saves 10%)
FiberMend is promoted as a multi-ingredient prebiotic supplement designed to maximize prebiotic activity. Meaning the blend can help feed and grow the beneficial bacteria in the digestive tract, which, in-turn,supports GI wellness. Thorne also claims that this product can:
Thorne is a company focused on the safety of their products, and all their products are third-party tested and GMP-certified through NSF. They also have an extensive list of ingredients they do not allow, including banned substances, fillers, additives, and allergens.
Fiber Blend. One one serving (11g scoop) of FiberMend contains several types of fiber that have been shown to help with gut health, including:
Green tea phytosome. While not a fiber, this ingredient is packed with antioxidants that may help support healthy prebiotic activity and can potentially neutralize free-radicals.
FiberMend is an unflavored, unsweetened powder, allowing you to mix it into any beverage or food without compromising taste. Customer reviews mention that it is a bit difficult to blend with cold liquids due to the clumping nature of fiber, but that it’s tasteless and easy to get down. While it may take a bit more planning to take a powder supplement when compared to a capsule, powders are generally easy to include in your everyday diet.
For most Americans, getting enough fiber, which is crucial to gut health, every day is difficult. Thorne FiberMend is a clean way to help close this gap, while getting a side of rich prebiotics. However, by design, FiberMend is not an all-inclusive option. For optimal gut health, you may want to consider additional supplements with probiotics and digestive enzymes.
Nutrition Fact: Consuming appropriate amounts of probiotics and fiber can also help preserve your gut lining, helping to knit the cells closer together.

MaryRuth’s Ultra Digestive Food is an enzyme-focused supplement from a company focused on delivering clean, high-quality products that are organic, non-GMO, vegetarian, and plant-based products.
Price per serving (with subscription): $7.48 (three tablets per day, one before each meal)
According to MaryRuth’s, Ultra Digestive Food Enzymes are formulated to support digestion and may help with the occasional bloating, gas, and feelings of fullness. This digestive enzyme supplement may also support a healthy immune system and contribute to your gut biome.
Like many of the other brands on our list, MaryRuth’s is focused on the quality of their products. This digestive enzyme complex is non-GMO, third-party tested, and manufactured in GMP-certified facilities in the U.S. The brand also boasts of a Clean Label Project certification, which shows their product is tested for over 200 toxins and contaminants.
This supplement contains 12+ digestive enzymes, including those that help break down carbohydrates, fats, proteins, fiber and lactose.
Enzyme blend: Protease blend, amylase blend, glucoamylase, invertase, pectinase, diastase, cellulase, hemicellulase, xylanase, lipase, lactase, alpha-galactosidase, beta-glucanase.
The capsule also includes B-vitamins like B6 and B12 that are recognized for their contribution to immune function.
Digestive enzymes work best when taken before eating, which is why MaryRuth’s recommends taking one tablet prior to each meal. So, you are looking at taking about 3 capsules a day, which can get tricky to remember.
As far as digestive enzymes go, MaryRuth’s Ultra Digestive Food Enzymes is an excellent option that provides digestion support to help break down all the different foods you may be consuming. With that said, digestive enzymes are just one part of our gut health puzzle, and the formula misses out on other pillars like prebiotics, probiotics, and dietary fiber
Your gut health is incredibly individual, and the supplement you choose should reflect this. No matter which supplement is right for your unique needs, there are specific features to look for (or avoid!), but, foremost, it’s best to chat with your healthcare provider before adding any new supplements into your daily routine.
Clean, high-quality supplements should be on everyone’s radar. Look for products that include all-natural, organic ingredients when possible.
If you know what specific gut-benefiting ingredient would work best for you, look for a supplement that focuses on that. If you’re unsure, consider an all-inclusive supplement, like Live it Up Super Greens, that incorporates plants, probiotics, fiber, and digestive enzymes to help cover your bases.
To help keep your GI tract happy and running smoothly, it’s worth avoiding ingredients that may cause more harm than good. Consider cutting back on artificial sweeteners and colors,fillers, preservatives, alongside sugar alcohols such as sorbitol and xylitol.
There is also some research implicating stevia extract in gut dysbiosis, which is an imbalance between the good and bad bacteria.
While choosing to take a gut health supplement is a great first step, the supplement needs to be dosed just right—not too little and not too much.
All of the supplements on our list come from companies with good quality control, however, not all supplement companies uphold the same standards. Make sure the supplement you choose is:
Follow these tips to support your digestive wellness, which starts with what you eat.
Choose a diet rich in plants, such as vegetables, fruits, whole grains, nuts, and seeds, will help keep a healthy diversity of good bacteria in your gut. These foods offer a wealth of fiber, antioxidants, vitamins, and minerals—all nutrients that support our gut health.
Choose foods rich in probiotics, such as yogurt with active cultures, kefir, kimchi, sauerkraut, tempeh, and miso. Adding these fermented foods may naturally support your gut microbiome.
Minimize certain foods, like processed meats, fried foods, ultra-processed snacks, and artificial sweeteners and colors, which can disrupt your digestive system and microbiome balance.
Additional tips to help keep your gut happy and digesting well:
The health of our gut impacts not only digestion, but many other aspects of our general wellness, like immune function and mood. Choosing the right gut health supplement starts with understanding your health goals and eating pattern.
Your gut needs all these things for optimal health! Since most people don’t know what they’re lacking or don’t want to take multiple supplements, my recommendation is to go with an all-encompassing product like Live it Up Super Greens that balances plants, probiotics, digestive enzymes, and fiber from prebiotic-rich vegetables.
Remember that what you eat every day is the most important strategy in helping to keep your gut healthy. Taking supplements can provide key support in areas you may be lacking.
Don't forget to chat with your healthcare provider about what supplement may work best for you.
Read on for a few more facts before you decide on the right health dietary supplement for you.
Signs of an unhealthy gut are bloating, gas, abdominal or stomach pain, and persistent bowel irritation or irregularity. Since gut health can also impact your mood and immune system, you may notice changes in these as well if your gut health isn’t up to par. Fatigue may also be a symptom to watch for if you aren't absorbing nutrients well.
If you suspect your gut is off balance, look at your overall diet to see where you can improve your intake and restore balance. Also, consider talking to a gut health dietitian like those at Top Nutrition Coaching to see if a gut health supplement can offer some support for gut wellness.
Improving your gut health starts with your diet and lifestyle habits. Follow an eating pattern with plenty of whole foods, including vegetables, fruits, whole grains, nuts, seeds, and beans for the micronutrients, antioxidants, amino acids, and fiber. Also, look to include probiotic-rich foods such as fermented foods and yogurt with active cultures. On the flip side, processed food, preservatives, additives, and artificial colors and sweeteners can take a toll on our gut, and those are the ingredients to be mindful of.
Alongside complementary and integrative health strategies, talk to a medical professional about how dietary supplements can step in to support areas where your diet is lacking. For example, taking probiotic products could help support your healthy microbiome, while a prebiotic fiber supplement can help fuel your beneficial bacteria. A digestive enzyme may help you better break down and absorb food.
Everyone’s gut health needs are individual, but a product with a holistic approach to gut health is often a good choice. These supplements have a multifaceted approach of ingredients that work synergistically, to help with gut health issues.
Rather than taking multiple supplements, some people opt for a comprehensive product such as Live it Up Super Greens, which combines more than 16 organic plants, 5 billion CFU probiotics, digestive enzymes, and 3 grams of fiber derived from vegetables rich in prebiotics. These are all components important for a healthy gut and digestion.
Other supplements in this round-up, such as VSL#3 or Thorne Fibermend, could also be a strong addition to your routine. With that said, everyone's health needs are different. If you have just finished a round of antibiotics, your healthcare provider may suggest probiotics to help replenish your beneficial bacteria colonies. Some probiotic products suggest benefits for women’s health.
Taking gut health supplements is not just for the health of your digestive system, but can impact overall wellness, including immune function, energy, and mood. So yes, it can be worth taking a gut health supplement, but also speak to a healthcare professional instead of self-diagnoising.
Also, look at your diet to see what you may be missing. Are you getting enough vegetables and plants but not enough probiotic-rich foods? Are you getting enough fiber but may need digestive enzymes?
Beginning your journey with a product that includes all the components important for gut health helps take the guesswork out of giving your gut (and your body) what it needs for optimal functioning. Interestingly, a healthy gut sustained with the right probiotics may positively impact bone health parameters and your urinary tract.
What you eat is critical to the overall health of your gut. Here are the top tips:

